Absolutely. Adobe Commerce is engineered specifically for global, multi-store, and multi-region commerce. You can manage multiple storefronts, brands, catalogs, currencies, and languages — all from a single backend. Region-specific pricing, localized content, tax rules, inventory splits, and custom buyer workflows are supported natively. For B2B enterprises operating across multiple countries, warehouse networks, or franchise structures, Magento provides the flexibility and governance needed to maintain consistency while enabling localized experiences.